Former Penn State Lacrosse player Chris Hogan scored a 37-yard touchdown for the Patriots, while fourth-string Christian Hackenberg warmed the bench this weekend.
Penn State is on a three-game winning streak heading into Big Ten play.
Penn State dominated the Explorers on its way to a third-straight win before the start of Big Ten play.
Russ Rose's Nittany Lions improved to 5-3 on the season thanks to a a pair of wins Saturday over Hofstra and tournament-host Syracuse.
Penn State didn't have enough to come back from a 2-0 halftime deficit against the Red Flash.
Erica Dambach's Nittany Lions controlled the entirety of their Friday evening match against San Diego State on the way to a second-straight win.