Jalen Pickett's 26 points and nine rebounds were not enough to complete the Nittany Lions' comeback attempt in Ann Arbor.
Kevin Wall and Liam Souliere have been an integral part of Penn State's success this season.
The Nittany Lions swept the CHA weekly awards following their series sweep over LIU.
Shay Ciezki scored a career-high 21 points despite Penn State falling
82-72 to No. 14 Michigan.
The Nittany Lions remain at No. 5 for the second consecutive poll.
A steal from Seth Lundy in the final moments helped secure the Nittany Lions' first win of 2023.