Josie Bothun was named the CHA Goaltender of the Month, while Maggie MacEachern was awarded the conference's Defensive Player of the Month accolade.
Three goals in the final 25 minutes of play lifted the Nittany Lions over the Bison after conceding a goal in the second minute.
The Nittany Lions are now 5-1-2 in overall play and 2-0 in conference matchups.
Shakes earned his third Big Ten weekly award of the season, while Mangione earned his first.