The Nittany Lions got off to a slow start and were never able to recover.
Designated hitter Josh Spiegel led the way offensively for the Nittany Lions, driving home four runs while going 4-for-5 at the plate.
Penn State's Saturday loss leaves it alone at the bottom of the Big Ten standings.
Sessoms will have one year of eligibility remaining as he joins MEAC-contending Coppin State.
Some sloppy fielding and underwhelming pitching led to Penn State's downfall Friday night against the Boilermakers.
Penn State's bats came alive this weekend in its series win.