Scoreless first periods and three losses highlighted the first half of the dual. However, the Nittany Lions dominated the end of the dual through several exciting close matchups.
The Nittany Lions' 56-game schedule will be headlined by a trip to PNC Park to challenge rival Pitt on May 17.
Penn State forced 20 turnovers, put up seven blocks, and tallied nine steals in Saturday's big win.
Penn State women's basketball's December 22 matchup against Towson has been canceled due to positive COVID-19 tests within Towson's program.
Penn State said the games against VCU and Quinnipiac won't be rescheduled.
The Nittany Lions' season will begin with a home matchup against Lafayette on February 5.